Search results for "Community onset"

showing 2 items of 2 documents

Carbapenem-Susceptible OXA-23-Producing Proteus mirabilis in the French Community

2019

International audience; Nineteen Proteus mirabilis isolates producing the carbapenemase OXA-23 were recovered over a 2-year period in 19 French hospitalized patients, of whom 12 had community onset infections. The isolates exhibited a slightly reduced susceptibility to carbapenems. Whole-genome analysis revealed that all 19 isolates formed a cluster compared to 149 other P. mirabilis isolates. Because of its susceptibility to carbapenems, this clone may be misidentified as a penicillinase producer while it constitutes a reservoir of the OXA-23-encoding gene in the community.

CarbapenemHospitalized patientsspreadclonalityMicrobial Sensitivity Testsbeta-LactamasesEpidemiology and SurveillanceMicrobiology03 medical and health sciencescarbapenemasemedicinepolycyclic compoundsHumansPharmacology (medical)Proteus mirabilis030304 developmental biologyCommunity onsetPharmacology0303 health sciencesbiologyOXA-23030306 microbiologybiochemical phenomena metabolism and nutritionbiology.organism_classificationProteus mirabilisAnti-Bacterial AgentsInfectious DiseasesReduced susceptibility[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyCarbapenemsbacteriaFranceProteus Infectionsmedicine.drug
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Community-onset Pseudomonas aeruginosa urinary sepsis in elderly people: Predictive factors, adequacy of empirical therapy and outcomes.

2019

Purpose To know the predictive factors for Pseudomonas aeruginosa (PA) urinary sepsis in hospitalised elderly patients coming from community, the adequacy of empirical antibiotic therapy and its outcomes. Methods Retrospective case-control study conducted between 2007 and 2017. Patients aged 65 years or older with PA urinary sepsis were included as cases. Three age-matched controls, with urinary sepsis caused by other microorganisms, were selected for each case. Predictors for PA urinary sepsis were determined by logistic regression analysis. Adequacy of empirical antibiotic therapy and outcomes were compared between both groups. Results A total of 332 patients, from which 83 were cases, we…

medicine.medical_specialtybusiness.industryPseudomonas aeruginosaUrinary systemGeneral Medicine030204 cardiovascular system & hematologymedicine.diseasemedicine.disease_causeLogistic regressionEmpirical antibiotic therapySepsis03 medical and health sciences0302 clinical medicineInternal medicinemedicineElderly people030212 general & internal medicinebusinessUrinary catheterCommunity onsetInternational journal of clinical practiceREFERENCES
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